Adam Cohen Selected Research

CNTO 528 monoclonal antibody

10/2008

A phase I, single and fractionated, ascending-dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietin mimetic antibody fusion protein (CNTO 528) in healthy male subjects.

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Adam Cohen Research Topics

Disease

7	Neoplasms (Cancer) 01/2018 - 11/2013
4	Multiple Myeloma 01/2022 - 01/2006
4	Type 2 Diabetes Mellitus (MODY) 01/2017 - 10/2006
4	Wounds and Injuries (Trauma) 08/2012 - 07/2009
2	Diarrhea 11/2018 - 01/2017
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Dementia (Dementias) 01/2022
1	Anxiety Disorders (Anxiety Disorder) 05/2019
1	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 01/2019
1	Bacterial Meningitis 01/2019
1	Meningitis 01/2019
1	Pulmonary Arterial Hypertension 10/2018
1	Glomerulonephritis 01/2018
1	Pain (Aches) 01/2018
1	Dupuytren Contracture (Dupuytrens Contracture) 01/2017
1	Paraganglioma (Paragangliomas) 01/2017
1	Low Back Pain (Lumbago) 01/2017
1	Meningioma (Meningiomas) 04/2016
1	Skin Neoplasms (Skin Cancer) 03/2016
1	Lymphoma (Lymphomas) 01/2016
1	Hematologic Neoplasms (Hematological Malignancy) 01/2016
1	Leukemia 01/2016
1	Glioblastoma (Glioblastoma Multiforme) 06/2015
1	Chromothripsis 06/2015
1	Glioma (Gliomas) 06/2015
1	Genomic Instability 06/2015
1	Pneumonia (Pneumonitis) 07/2013
1	Hallux Rigidus 07/2012
1	Osteoarthritis 07/2012
1	Burns 07/2010
1	Anemia 10/2008
1	Seizures (Absence Seizure) 08/2007
1	Epilepsy (Aura) 08/2007
1	Inflammation (Inflammations) 10/2006
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2006

Drug/Important Bio-Agent (IBA)

2	Conjugate VaccinesIBA 01/2019 - 07/2013
2	Rotavirus VaccinesIBA 11/2018 - 01/2017
2	Dexamethasone (Maxidex)FDA LinkGeneric 02/2012 - 01/2006
2	Thalidomide (Thalomid)FDA Link 02/2012 - 01/2006
2	Biomarkers (Surrogate Marker)IBA 05/2007 - 10/2006
2	ThiazolidinedionesIBA 05/2007 - 10/2006
2	Rosiglitazone (Avandia)FDA Link 05/2007 - 10/2006
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2022
1	Galantamine (Galanthamine)FDA LinkGeneric 01/2022
1	Cholinergic Agents (Cholinergics)IBA 01/2022
1	gamma-Aminobutyric Acid (GABA)IBA 05/2019
1	GABA-A Receptors (GABA(A) Receptor)IBA 05/2019
1	VaccinesIBA 01/2019
1	Bacterial VaccinesIBA 01/2019
1	treprostinil FDA Link 10/2018
1	Immunoglobulins (Immunoglobulin)IBA 01/2018
1	Pharmaceutical PreparationsIBA 11/2017
1	ProteomeIBA 11/2017
1	inulin trinicotinate monomethochloride (L-3)IBA 01/2017
1	fluorodopa F 18IBA 01/2017
1	Capecitabine (Xeloda)FDA Link 01/2017
1	Temozolomide (Temodar)FDA LinkGeneric 01/2017
1	Insulin (Novolin)FDA Link 01/2017
1	Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric 01/2017
1	Collagenases (Collagenase)FDA Link 01/2017
1	ISIS 388626IBA 11/2016
1	Sodium-Glucose Transport ProteinsIBA 11/2016
1	Sodium-Glucose Transporter 2 InhibitorsIBA 11/2016
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2016
1	Somatostatin Receptors (Somatostatin Receptor)IBA 04/2016
1	Interferon-alpha (Interferon Alfa)IBA 04/2016
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 06/2015
1	DNA (Deoxyribonucleic Acid)IBA 06/2015
1	Biological ProductsIBA 06/2015
1	CyclinsIBA 06/2015
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 06/2015
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 06/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2013
1	GlucocorticoidsIBA 11/2013
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 11/2013
1	Transcription Factors (Transcription Factor)IBA 11/2013
1	Bortezomib (Velcade)FDA Link 02/2012
1	7,7'- dimethoxy- (4,4'- bi- 1,3- benzodioxole)- 5,5'- dicarboxylic acid dimethyl ester (BDD)IBA 02/2012
1	liposomal doxorubicin (Doxil)FDA Link 02/2012
1	CNTO 528 monoclonal antibodyIBA 10/2008
1	Erythropoietin FDA Link 10/2008
1	Pregabalin (Lyrica)FDA Link 08/2007
1	CytokinesIBA 10/2006
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2006
1	Drug CombinationsIBA 01/2006
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2006

Therapy/Procedure

8	Therapeutics 01/2022 - 01/2006
2	Radiotherapy 01/2018 - 01/2017
2	Cardiac Catheters 08/2012 - 05/2011
1	Analgesia 01/2018
1	Drug Therapy (Chemotherapy) 01/2018
1	Injections 01/2017
1	Operative Surgical Procedures 03/2016
1	Immunotherapy 01/2016
1	Ligation 11/2013
1	Arthroplasty 07/2012
1	Skin Transplantation (Skin Grafting) 07/2010
1	Tissue Expansion 07/2009
1	Autologous Transplantation 07/2009
1	Intravenous Administration 10/2008